Entries Tagged 'Vocabularies' ↓

Understanding International Statistical Classification of Diseases (ICD)

This a next installment of the Understanding terminologies series.

I’ll try to keep this post short, give a general overview of International Statistical classification of Disease (ICD), talk a little about ICD-9 & ICD-10 and leave your folks will links to practical advise on converting from ICD-9 to ICD-10, and SNOMED-CT to ICD-10.

Continue reading →

Understanding Components of CCD

Connectivity of Care Document (CCD) is a collaborative standard driven by HL7 & ASTM for exchanging summary format clinical information.

For ease of understanding one can think of CCD standard comprising of several elements in an hierarchical fashion:

  1. HL7 V3 Data Types and Reference Information Model (RIM) : At the base of CCD standard are the HL7 Data types and Reference Information Model.  HL7 V3 data types define the structural format of the data carried. The HL7 RIM expresses the information content of work done by HL7 working committee to define data types, relationships between them, and a state transition model for some entities.
  2. Clinical Document Architecture (CDA): The HL7 CDA defines the specific structure and semantics for any clinical document for purposes of exchange. CDA document can be encoded in XML. A CDA document if encoded in XML must comply to the schema. NIST has a good CDA validation tool.
  3. CCD Implementation Guide: The CCD implementation guide describes the constraints on the HL7 Clinical Document Architecture R2 specification in accordance with requirements set forward by ASTM (the governing body behind CCR).

image

Fig 1. Components of CCD Standard

Related articles in this series :

  1. Understanding Vocabularies. Wait! What did you say?
  2. Understanding Vocabularies #2 – HealthVault Recommendations
  3. Understanding SNOMED CT
  4. Understanding CCR

Understanding CCR

Update: Fixed typos, added links to related tools and articles, updated the example.

CCR or Continuity of Care Record is a standard meant to ease the exchange of clinical information with a relatively easy to read and practical data-format and schema. There is ton of great information about CCR on its resource site. CCR document format is supported by majority of personal Health clouds, both – Microsoft HealthVault & Google Health.

The CCR specification comprises an implementation guide, XML schema definition and a guidance spreadsheet for each data element that makes up the standard. These resources can be bought from ASTM.

The document format of CCR is very straight forward, consisting of a header, body and a footer with the following top-level elements:

Header Body Body Footer
  • CCR Document ID
  • Language
  • Version
  • Creation Date
  • Patient
  • From
  • To
  • Purpose
  • Payers
  • Advance Directives
  • Support
  • Functional Status
  • Problems
  • Family History
  • Social History
  • Alerts
  • Medications
  • Medical Equipment
  • Immunizations
  • Vital Signs
  • Results
  • Procedures
  • Encounters
  • Plan Of Care
  • HealthCareProviders
  • Actors
  • Signatures
  • References
  • Comments
  •  

    Google Health supports only a limited set of entities from the above, while HealthVault supports the entire standard and also allows transformation of some of these entities in to native HealthVault types. You can read more about working with CCR in HealthVault and various input mappings, output mappings, and CCR vocabularies.

    Here are some illustrative CCR figures from Dr. Waldren’s presentation (see end of article).

    image image

    Using the SNOMED-CT concepts one can write the Systolic Blood pressure reading in CCR as the following (UPDATE: Well-formatted the CCR to include source, object-id and actors, thanks to Matt Wagner):

    <?xml version="1.0" encoding="utf-8"?>
    <ContinuityOfCareRecord xmlns='urn:astm-org:CCR'>
      <CCRDocumentObjectID>Doc</CCRDocumentObjectID>
      <Language>
        <Text>English</Text>
      </Language>
      <Version>V1.0</Version>
      <DateTime>
        <ExactDateTime>2008</ExactDateTime>
      </DateTime>
      <Patient>
        <ActorID>Patient</ActorID>
      </Patient>
      <Body>
        <VitalSigns>
          <Result>
            <CCRDataObjectID>0001</CCRDataObjectID>
            <Description>
              <Text>Blood Pressure</Text>
            </Description>
            <Source>
              <Description>
                <Text>Unknown</Text>
              </Description>
            </Source>
            <Test>
              <CCRDataObjectID>0002</CCRDataObjectID>
              <Description>
                <Text>Systolic</Text>
                <Code>
                  <Value>163030003</Value>
                  <CodingSystem>SNOMEDCT</CodingSystem>
                </Code>
              </Description>
              <Source>
                <Description>
                  <Text>Unknown</Text>
                </Description>
              </Source>
              <TestResult>
                <Value>120</Value>
                <Units>
                  <Unit>mmHg</Unit>
                </Units>
              </TestResult>
            </Test>
            <Test>
              <CCRDataObjectID>0003</CCRDataObjectID>
              <Description>
                <Text>Diastolic</Text>
                <Code>
                  <Value>163031004</Value>
                  <CodingSystem>SNOMEDCT</CodingSystem>
                </Code>
              </Description>
              <Source>
                <Description>
                  <Text>Unknown</Text>
                </Description>
              </Source>
              <TestResult>
                <Value>75</Value>
                <Units>
                  <Unit>mmHg</Unit>
                </Units>
              </TestResult>
            </Test>
          </Result>
        </VitalSigns>
      </Body>
      <Actors>
        <Actor>
          <ActorObjectID>Patient</ActorObjectID>
          <Person>
            <Name>
              <CurrentName>
                <Given>John</Given>
                <Family>Doe</Family>
              </CurrentName>
            </Name>
          </Person>
          <Source>
            <Description>
              <Text>Unknown</Text>
            </Description>
          </Source>
        </Actor>
      </Actors>
    </ContinuityOfCareRecord>
    

    Note CodingSystem element. It allows CCR to interpret various medical vocabularies.

    Relevant Tools:

    (Thanks to Kathleen Connor)

    • The CCR Validator, is an important resource to test/validate a CCR instance, is a now available  Not only does it validate the CCR against the XSD but also the constraints of the implementation guide.
    • An Open Source StyleSheet to view CCR files.
    • CCR to CCD & HL7 Mappers – tools which Map CCR to CCD and HL7 V2 & V3. You can access them directly here.
    • Application to embed CCR in PDF-HealthCare.

    Related Article(s):

    • To get familiar with CCR I would highly recommended this 13 minute video by Dr. Steve Waldren.
    • Adam Bosworth posted an interesting read on standards, his take (simple, human readable, focus on known structured data, etc.) favors CCR.

    In this series:

    1. Understanding Vocabularies. Wait! What did you say?
    2. Understanding Vocabularies #2 – HealthVault Recommendations
    3. Understanding SNOMED CT
    4. Understanding CCR
    Special thanks to Kathy Osborne for proof reading this post.

    Understanding SNOMED CT

    I have previously posted about Understanding Health Ontologies and Standards. In this post I’ll focus on SNOMED-CT (Systematized Nomenclature of Medicine Clinical Terms). SNOMED-CT is the most comprehensive vocabulary to express clinical terms – it spans languages, specialties and geographic borders.

    SNOMED-CT includes:

    • Terms or synonyms relating to a clinical concept
    • Links between different concepts

    To give you a taste here is an example of Blood pressure reading represented using SNOMED-CT from the linked paper (“Towards semantic interoperability in healthcare: ontology mapping from SNOMED-CT to HL7 version 3”, Amanda Ryan):

    Ontology_Mapping

    In addition to having a model to represent concepts and linkages the biggest draw of SNOMED CT is a staggering number of coded qualifiers (which belong to one concept or other). According to IHTSO there are about 311,000 actively used SNOMED CT concepts.

    You can register for SNOMED CT here. Its free for companies and individuals in United States, however your registration is processed by NLM and it might take over 3 days to receive a confirmation and access.

    Once you are through with registration and have an account, start by downloading the core subset of SNOMED CT concepts here, this list consists of about 5000 most frequently used terms by institutions across US. Its a good set to get familiar with, it consists of the following concept area:

    • Clinical finding        : 4,550 codes in total
    • Procedure            :   414 codes in total
    • Situation with explicit context    :   132 codes in total
    • Event                :    38 codes in total
    • Body structure            :    46 codes in total
    • Social context            :     2 codes in total

    Snomed_Subset

    We can use BCP to copy the files from SNOMED CT Core in to our local database, and do more interesting queries & data analysis like find distribution on these terms, co-relate problems vs. findings and of course work on the larger SNOMED CT database to find synonyms etc.; but I’ll keep that for another day. Here very quickly I’ll show how one can use a web-based browser, Snowflake, http://snomed.dataline.co.uk/ (requires registration) to lookup a SNOMED code and see what else it relates to. We can see that in line 3 above SNOMED CT concept 10085004 is marked as Metatarsalgia (finding), however using the Snowflake browser we can see in that in addition to being a finding this concept is a problem as well.

    Snomed_Snowflake

    This was just tip of the ice-berg, please leave comments for future posts / areas to consider in the Ontology domain.

    Further reading / relevant links:

    In this series:

    1. Understanding Vocabularies. Wait! What did you say?
    2. Understanding Vocabularies #2 – HealthVault Recommendations
    3. Understanding SNOMED CT

    Understanding Vocabularies #2 – HealthVault Recommendations

    In my last article in the vocabulary category, I described the need for semantically enabled data and how different categories of health data have different standard vocabulary / ontology associated with them. In the following table I attempt to summarize the recommended vocabularies for different HealthVault types.

    Disclaimer: Please note this is not a definitive or complete list, and I will update the table as I discover inconsistencies. The definitive source are the XSDs associated with HealthVault data types.

    HealthVault Type Type Schema HV Recommended vocabulary related to this type Comments
    Advance Directive 822a5e5a-14f1-4d06-b92f-8f3f1b05218f None

    Examples include living wills and power of attorney for healthcare.

    Allergy 52bf9104-2c5e-4f1f-a66d-552ebcc53df7 icd9cm, icd9cm-reactions Details on ICD-9 Codes
    Basic Demographic Information bf516a61-5252-4c28-a979-27f45f62f78d ISO-3166 Country of residence
    Blood Glucose Measurement

    879e7c04-4e8a-4707-9ad3-b054df467ce4

    glucose-measurement-type  
    Blood Oxygen Saturation

    3a54f95f-03d8-4f62-815f-f691fc94a500

    blood-oxygen-saturation-measurement-method  
    Body Composition

    18adc276-5144-4e7e-bf6c-e56d8250adf8

    body-composition-measurement-methods  
    Body Dimension dd710b31-2b6f-45bd-9552-253562b9a7c1 body-dimension-measurement-names, body-dimension-measurement-names-pediatric  
    Calorie Guideline

    d3170d30-a41b-4bde-a116-87698c8a001a

    calorie-guideline-names  
    Concern aea2e8f2-11dd-4a7d-ab43-1d58764ebc19 concern-description Concerns are more general than conditions
    Condition 7ea7a1f9-880b-4bd4-b593-f5660f20eda8    
    Continuity of Care Document (CCD)

    9c48a2b8-952c-4f5a-935d-f3292326bf54

       
    Continuity of Care Record (CCR)

    1e1ccbfc-a55d-4d91-8940-fa2fbf73c195

      http://www.ccrstandard.com/
    Daily Medication Usage a9a76456-0357-493e-b840-598bbb9483fd dose-purpose, usage-schedule, x12-de-1330, prescription-type, x12-d3-355,  
    Diabetes Insulin Injection Use

    184166be-8adb-4d9c-8162-c403040e31ad

    insulin-types,  
    Discharge Summary

    02ef57a2-a620-425a-8e92-a301542cca54

    icd9cm  
    HbA1C Measurement

    227f55fb-1001-4d4e-9f6a-8d893e07b451

    HbA1C-assay-method  
    Health Assessment

    58fd8ac4-6c47-41a3-94b2-478401f0e26c

    health-assessment-name, health-assessment-value-sets, health-assessment-groups, health-assessment-category  
    Heart Rate b81eb4a6-6eac-4292-ae93-3872d6870994 heart-rate-measurement-conditions  
    HL7 Clinical Document Architecture, Release 2

    1ed1cba6-9530-44a3-b7b5-e8219690ebcf

       
    Immunization

    cd3587b5-b6e1-4565-ab3b-1c3ad45eb04f

    vaccines-cvx, vaccine-manufacturers-mvx, medication-routes,  
    Insulin Injection

    3b3c053b-b1fe-4e11-9e22-d4b480de74e8

    insulin-types  
    Insurance Plan

    9366440c-ec81-4b89-b231-308a4c4d70ed

    coverage-types  
    Lab Test Results

    f57746af-9631-49dc-944e-2c92bee0d1e9

    LOINC, lab-status, lab-results-flag, More on LOINC here.
    Medication 30cafccc-047d-4288-94ef-643571f7919d Rxnorm, NDC, medication-prescribed  
    Medication Fill

    167ecf6b-bb54-43f9-a473-507b334907e0

    Rxnorm, NDC  
    Personal Demographic Information

    92ba621e-66b3-4a01-bd73-74844aed4f5b

    blood-types, ethnicity, marital-status, religion, education-level,  
    Pregnancy 46d485cf-2b84-429d-9159-83152ba801f4 delivery-complications, anesthesia-methods, delivery-methods, pregnancy-outcomes, gender-types, conception-methods,  
    Question Answer 55d33791-58de-4cae-8c78-819e12ba5059 question-sets, answer-choice-sets  
    Sleep Related Activity

    031f5706-7f1a-11db-ad56-7bd355d89593

     

    November 2005, "Your Guide to Healthy Sleep", ISBN 1-933236-05-1

    Sleep Session

    11c52484-7f1a-11db-aeac-87d355d89593

     

    November 2005, "Your Guide to Healthy Sleep", ISBN 1-933236-05-1

    Vital Signs

    73822612-c15f-4b49-9e65-6af369e55c65

    lab-results-units, lab-results-flag,  

     

    As  you can notice above we recommend ICD-9, RxNorm, LOINC, NDC. x12-de-1130, x12-de-335. We do prefer SNOMED-CT as well, however the application using it need to have license for it.

    Having written the above I would like to match that with what Dr. Halamka recommends in his post. Note that I mention content column for completeness, however its not useful for comparison.

    Data Content Vocabulary
    Demographics HL7 2.x for messaging, CCD for document summaries HITSP Harmonized code sets for gender, marital status
    Problem List HL7 2.x for messaging, CCD for document summaries SNOMED-CT
    Medications NCPDP script for messaging, CCD for document summaries RxNorm and Structured SIG
    Allergies HL7 2.x for messaging, CCD for document summaries UNII for foods and substances, NDF-RT for medication class, RxNorm for Medications
    Progress Notes and Other Narrative Documents (History and Physical, Operative Notes, Discharge Summary) HL7 2.x for messaging, CCD for document summaries CDA Templates (interesting note)
    Departmental Reports (Pathology/Cytology, GI, Pulmonary, Cardiology etc.) HL7 2.x for messaging, CCD for document summaries SNOMED-CT
    Laboratory Results HL7 2.x for messaging, CCD for document summaries LOINC for lab name, UCUM for units of measure, SNOMED-CT for test ordering reason
    Microbiology HL7 2.x for messaging, CCD for document summaries LOINC for lab name/observation
    Images DICOM  
    Administrative Transactions (Benefits/Eligibility, Referral/Authorization, Claims/Remittance) X12 X12, CAQH CORE

    Next Time: I’ll try to update the above tables with more details and try to come with recommendations of which clinical type (in the Data column above) would potentially match with which HealthVault type.

    As usual leave your suggestions in the comments.